diff --git a/libpod/runtime.go b/libpod/runtime.go
index 4c7d06f1f9..73c607ad48 100644
--- a/libpod/runtime.go
+++ b/libpod/runtime.go
@@ -369,6 +369,14 @@ func makeRuntime(ctx context.Context, runtime *Runtime) (retErr error) {
 		return fmt.Errorf("creating runtime temporary files directory: %w", err)
 	}
 
+	// Create the volume path if needed.
+	// This is not strictly necessary at this point, but the path not
+	// existing can cause troubles with DB path validation on OSTree based
+	// systems. Ref: https://github.com/containers/podman/issues/23515
+	if err := os.MkdirAll(runtime.config.Engine.VolumePath, 0700); err != nil {
+		return fmt.Errorf("creating runtime volume path directory: %w", err)
+	}
+
 	// Set up the state.
 	runtime.state, err = getDBState(runtime)
 	if err != nil {
diff --git a/test/system/005-info.bats b/test/system/005-info.bats
index baf34a8ece..c4ad5c32f8 100644
--- a/test/system/005-info.bats
+++ b/test/system/005-info.bats
@@ -194,6 +194,13 @@ host.slirp4netns.executable | $expr_path
 
     ln -s /home $new_home
 
+    # Remove volume directory. This doesn't break Podman but can cause our DB
+    # validation to break if Podman misbehaves. Ref:
+    # https://github.com/containers/podman/issues/23515
+    # (Unfortunately, we can't just use a new directory, that will just trip DB
+    # validation that it doesn't match the path we were using before)
+    rm -rf $PODMAN_TMPDIR/$HOME/.local/share/containers/storage/volumes
+
     # Just need the command to run cleanly
     HOME=$PODMAN_TMPDIR/$HOME run_podman info