diff --git a/dev-requirements.txt b/dev-requirements.txt
index 5b53cd381..4bc1bde99 100644
--- a/dev-requirements.txt
+++ b/dev-requirements.txt
@@ -13,3 +13,4 @@ readme-renderer~=24.0
 grpcio-tools==1.29.0
 mypy-protobuf>=1.23
 protobuf>=3.13.0
+markupsafe==2.0.1
diff --git a/docs-requirements.txt b/docs-requirements.txt
index 1a5f7d0cb..f9a9a13f7 100644
--- a/docs-requirements.txt
+++ b/docs-requirements.txt
@@ -37,3 +37,5 @@ sqlalchemy>=1.0
 tornado>=5.1.1
 ddtrace>=0.34.0
 httpx>=0.18.0
+markupsafe==2.0.1
+itsdangerous==2.0.1
\ No newline at end of file
diff --git a/gen-requirements.txt b/gen-requirements.txt
index d4a52e0da..bba15feb2 100644
--- a/gen-requirements.txt
+++ b/gen-requirements.txt
@@ -1,6 +1,7 @@
 -c dev-requirements.txt
 astor==0.8.1
 jinja2~=2.7
+markupsafe==2.0.1
 isort
 black
 requests
diff --git a/instrumentation/opentelemetry-instrumentation-boto/setup.cfg b/instrumentation/opentelemetry-instrumentation-boto/setup.cfg
index b80e12b7c..03639951f 100644
--- a/instrumentation/opentelemetry-instrumentation-boto/setup.cfg
+++ b/instrumentation/opentelemetry-instrumentation-boto/setup.cfg
@@ -48,6 +48,7 @@ install_requires =
 test =
     moto~=2.0
     opentelemetry-test-utils == 0.28b1
+    markupsafe==2.0.1
 
 [options.packages.find]
 where = src
diff --git a/instrumentation/opentelemetry-instrumentation-botocore/setup.cfg b/instrumentation/opentelemetry-instrumentation-botocore/setup.cfg
index 64ef81f12..261ad302d 100644
--- a/instrumentation/opentelemetry-instrumentation-botocore/setup.cfg
+++ b/instrumentation/opentelemetry-instrumentation-botocore/setup.cfg
@@ -48,6 +48,7 @@ install_requires =
 test =
     moto[all] ~= 2.2.6
     opentelemetry-test-utils == 0.28b1
+    markupsafe==2.0.1
 
 [options.packages.find]
 where = src
diff --git a/instrumentation/opentelemetry-instrumentation-flask/setup.cfg b/instrumentation/opentelemetry-instrumentation-flask/setup.cfg
index 9a14ed20e..d71bd4165 100644
--- a/instrumentation/opentelemetry-instrumentation-flask/setup.cfg
+++ b/instrumentation/opentelemetry-instrumentation-flask/setup.cfg
@@ -49,6 +49,7 @@ install_requires =
 [options.extras_require]
 test =
     opentelemetry-test-utils == 0.28b1
+    markupsafe==2.0.1
 
 [options.entry_points]
 opentelemetry_instrumentor =
diff --git a/instrumentation/opentelemetry-instrumentation-jinja2/setup.cfg b/instrumentation/opentelemetry-instrumentation-jinja2/setup.cfg
index 63dff62b6..97588f6ef 100644
--- a/instrumentation/opentelemetry-instrumentation-jinja2/setup.cfg
+++ b/instrumentation/opentelemetry-instrumentation-jinja2/setup.cfg
@@ -46,6 +46,7 @@ install_requires =
 [options.extras_require]
 test =
     opentelemetry-test-utils == 0.28b1
+    markupsafe==2.0.1
 
 [options.packages.find]
 where = src