diff --git a/instrumentation/opentelemetry-instrumentation-fastapi/CHANGELOG.md b/instrumentation/opentelemetry-instrumentation-fastapi/CHANGELOG.md
new file mode 100644
index 000000000..c8c5cea0d
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-fastapi/CHANGELOG.md
@@ -0,0 +1,9 @@
+# Changelog
+
+## Unreleased
+
+## Version 0.11b0
+
+Released 2020-07-28
+
+- Initial release ([#890](https://github.com/open-telemetry/opentelemetry-python/pull/890))
\ No newline at end of file
diff --git a/instrumentation/opentelemetry-instrumentation-fastapi/README.rst b/instrumentation/opentelemetry-instrumentation-fastapi/README.rst
new file mode 100644
index 000000000..4cc612da7
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-fastapi/README.rst
@@ -0,0 +1,43 @@
+OpenTelemetry FastAPI Instrumentation
+=======================================
+
+|pypi|
+
+.. |pypi| image:: https://badge.fury.io/py/opentelemetry-instrumentation-fastapi.svg
+   :target: https://pypi.org/project/opentelemetry-instrumentation-fastapi/
+
+
+This library provides automatic and manual instrumentation of FastAPI web frameworks,
+instrumenting http requests served by applications utilizing the framework.
+
+auto-instrumentation using the opentelemetry-instrumentation package is also supported.
+
+Installation
+------------
+
+::
+
+    pip install opentelemetry-instrumentation-fastapi
+
+
+Usage
+-----
+
+.. code-block:: python
+
+    import fastapi
+    from opentelemetry.instrumentation.fastapi import FastAPIInstrumentor
+
+    app = fastapi.FastAPI()
+
+    @app.get("/foobar")
+    async def foobar():
+        return {"message": "hello world"}
+
+    FastAPIInstrumentor.instrument_app(app)
+
+
+References
+----------
+
+* `OpenTelemetry Project <https://opentelemetry.io/>`_
\ No newline at end of file
diff --git a/instrumentation/opentelemetry-instrumentation-fastapi/setup.cfg b/instrumentation/opentelemetry-instrumentation-fastapi/setup.cfg
new file mode 100644
index 000000000..f4c64744f
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-fastapi/setup.cfg
@@ -0,0 +1,55 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+#
+[metadata]
+name = opentelemetry-instrumentation-fastapi
+description = OpenTelemetry FastAPI Instrumentation
+long_description = file: README.rst
+long_description_content_type = text/x-rst
+author = OpenTelemetry Authors
+author_email = cncf-opentelemetry-contributors@lists.cncf.io
+url = https://github.com/open-telemetry/opentelemetry-python/tree/master/instrumentation/opentelemetry-instrumentation-fastapi
+platforms = any
+license = Apache-2.0
+classifiers =
+    Development Status :: 4 - Beta
+    Intended Audience :: Developers
+    License :: OSI Approved :: Apache Software License
+    Programming Language :: Python
+    Programming Language :: Python :: 3
+    Programming Language :: Python :: 3.6
+    Programming Language :: Python :: 3.7
+    Programming Language :: Python :: 3.8
+
+[options]
+python_requires = >=3.6
+package_dir=
+    =src
+packages=find_namespace:
+install_requires =
+    opentelemetry-api == 0.12.dev0
+    opentelemetry-instrumentation-asgi == 0.12.dev0
+
+[options.entry_points]
+opentelemetry_instrumentor =
+    fastapi = opentelemetry.instrumentation.fastapi:FastAPIInstrumentor
+
+[options.extras_require]
+test =
+    opentelemetry-test == 0.12.dev0
+    fastapi ~= 0.58.1
+    requests ~= 2.23.0 # needed for testclient
+
+[options.packages.find]
+where = src
diff --git a/instrumentation/opentelemetry-instrumentation-fastapi/setup.py b/instrumentation/opentelemetry-instrumentation-fastapi/setup.py
new file mode 100644
index 000000000..13c7c5a99
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-fastapi/setup.py
@@ -0,0 +1,31 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+import os
+
+import setuptools
+
+BASE_DIR = os.path.dirname(__file__)
+VERSION_FILENAME = os.path.join(
+    BASE_DIR,
+    "src",
+    "opentelemetry",
+    "instrumentation",
+    "fastapi",
+    "version.py",
+)
+PACKAGE_INFO = {}
+with open(VERSION_FILENAME) as f:
+    exec(f.read(), PACKAGE_INFO)
+
+setuptools.setup(version=PACKAGE_INFO["__version__"])
diff --git a/instrumentation/opentelemetry-instrumentation-fastapi/src/opentelemetry/instrumentation/fastapi/__init__.py b/instrumentation/opentelemetry-instrumentation-fastapi/src/opentelemetry/instrumentation/fastapi/__init__.py
new file mode 100644
index 000000000..57c9a5bfc
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-fastapi/src/opentelemetry/instrumentation/fastapi/__init__.py
@@ -0,0 +1,82 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+from typing import Optional
+
+import fastapi
+from starlette.routing import Match
+
+from opentelemetry.instrumentation.asgi import OpenTelemetryMiddleware
+from opentelemetry.instrumentation.fastapi.version import __version__  # noqa
+from opentelemetry.instrumentation.instrumentor import BaseInstrumentor
+
+
+class FastAPIInstrumentor(BaseInstrumentor):
+    """An instrumentor for FastAPI
+
+    See `BaseInstrumentor`
+    """
+
+    _original_fastapi = None
+
+    @staticmethod
+    def instrument_app(app: fastapi.FastAPI):
+        """Instrument an uninstrumented FastAPI application.
+        """
+        if not getattr(app, "is_instrumented_by_opentelemetry", False):
+            app.add_middleware(
+                OpenTelemetryMiddleware,
+                span_details_callback=_get_route_details,
+            )
+            app.is_instrumented_by_opentelemetry = True
+
+    def _instrument(self, **kwargs):
+        self._original_fastapi = fastapi.FastAPI
+        fastapi.FastAPI = _InstrumentedFastAPI
+
+    def _uninstrument(self, **kwargs):
+        fastapi.FastAPI = self._original_fastapi
+
+
+class _InstrumentedFastAPI(fastapi.FastAPI):
+    def __init__(self, *args, **kwargs):
+        super().__init__(*args, **kwargs)
+        self.add_middleware(
+            OpenTelemetryMiddleware, span_details_callback=_get_route_details
+        )
+
+
+def _get_route_details(scope):
+    """Callback to retrieve the fastapi route being served.
+
+    TODO: there is currently no way to retrieve http.route from
+    a starlette application from scope.
+
+    See: https://github.com/encode/starlette/pull/804
+    """
+    app = scope["app"]
+    route = None
+    for starlette_route in app.routes:
+        match, _ = starlette_route.matches(scope)
+        if match == Match.FULL:
+            route = starlette_route.path
+            break
+        if match == Match.PARTIAL:
+            route = starlette_route.path
+    # method only exists for http, if websocket
+    # leave it blank.
+    span_name = route or scope.get("method", "")
+    attributes = {}
+    if route:
+        attributes["http.route"] = route
+    return span_name, attributes
diff --git a/instrumentation/opentelemetry-instrumentation-fastapi/src/opentelemetry/instrumentation/fastapi/version.py b/instrumentation/opentelemetry-instrumentation-fastapi/src/opentelemetry/instrumentation/fastapi/version.py
new file mode 100644
index 000000000..780a92b6a
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-fastapi/src/opentelemetry/instrumentation/fastapi/version.py
@@ -0,0 +1,15 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+__version__ = "0.12.dev0"
diff --git a/instrumentation/opentelemetry-instrumentation-fastapi/tests/__init__.py b/instrumentation/opentelemetry-instrumentation-fastapi/tests/__init__.py
new file mode 100644
index 000000000..e69de29bb
diff --git a/instrumentation/opentelemetry-instrumentation-fastapi/tests/test_fastapi_instrumentation.py b/instrumentation/opentelemetry-instrumentation-fastapi/tests/test_fastapi_instrumentation.py
new file mode 100644
index 000000000..47617d4e9
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-fastapi/tests/test_fastapi_instrumentation.py
@@ -0,0 +1,104 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+import unittest
+
+import fastapi
+from fastapi.testclient import TestClient
+
+import opentelemetry.instrumentation.fastapi as otel_fastapi
+from opentelemetry.test.test_base import TestBase
+
+
+class TestFastAPIManualInstrumentation(TestBase):
+    def _create_app(self):
+        app = self._create_fastapi_app()
+        self._instrumentor.instrument_app(app)
+        return app
+
+    def setUp(self):
+        super().setUp()
+        self._instrumentor = otel_fastapi.FastAPIInstrumentor()
+        self._app = self._create_app()
+        self._client = TestClient(self._app)
+
+    def test_basic_fastapi_call(self):
+        self._client.get("/foobar")
+        spans = self.memory_exporter.get_finished_spans()
+        self.assertEqual(len(spans), 3)
+        for span in spans:
+            self.assertIn("/foobar", span.name)
+
+    def test_fastapi_route_attribute_added(self):
+        """Ensure that fastapi routes are used as the span name."""
+        self._client.get("/user/123")
+        spans = self.memory_exporter.get_finished_spans()
+        self.assertEqual(len(spans), 3)
+        for span in spans:
+            self.assertIn("/user/{username}", span.name)
+        self.assertEqual(
+            spans[-1].attributes["http.route"], "/user/{username}"
+        )
+        # ensure that at least one attribute that is populated by
+        # the asgi instrumentation is successfully feeding though.
+        self.assertEqual(spans[-1].attributes["http.flavor"], "1.1")
+
+    @staticmethod
+    def _create_fastapi_app():
+        app = fastapi.FastAPI()
+
+        @app.get("/foobar")
+        async def _():
+            return {"message": "hello world"}
+
+        @app.get("/user/{username}")
+        async def _(username: str):
+            return {"message": username}
+
+        return app
+
+
+class TestAutoInstrumentation(TestFastAPIManualInstrumentation):
+    """Test the auto-instrumented variant
+
+    Extending the manual instrumentation as most test cases apply
+    to both.
+    """
+
+    def _create_app(self):
+        # instrumentation is handled by the instrument call
+        self._instrumentor.instrument()
+        return self._create_fastapi_app()
+
+    def tearDown(self):
+        self._instrumentor.uninstrument()
+        super().tearDown()
+
+
+class TestAutoInstrumentationLogic(unittest.TestCase):
+    def test_instrumentation(self):
+        """Verify that instrumentation methods are instrumenting and
+        removing as expected.
+        """
+        instrumentor = otel_fastapi.FastAPIInstrumentor()
+        original = fastapi.FastAPI
+        instrumentor.instrument()
+        try:
+            instrumented = fastapi.FastAPI
+            self.assertIsNot(original, instrumented)
+        finally:
+            instrumentor.uninstrument()
+
+        should_be_original = fastapi.FastAPI
+        self.assertIs(original, should_be_original)