diff --git a/CHANGELOG.md b/CHANGELOG.md
index c4d2d1dad..35c158b6d 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -7,6 +7,11 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ## [Unreleased](https://github.com/open-telemetry/opentelemetry-python/compare/v1.6.0-0.25b0...HEAD)
 
+### Changed
+- `opentelemetry-util-http` no longer contains an instrumentation entrypoint and will not be loaded
+automatically by the auto instrumentor.
+([#745](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/745))
+
 ## [1.6.0-0.25b0](https://github.com/open-telemetry/opentelemetry-python/releases/tag/v1.6.0-0.25b0) - 2021-10-13
 
 
diff --git a/util/opentelemetry-util-http/setup.cfg b/util/opentelemetry-util-http/setup.cfg
index 9b3f4b411..6e8c78f32 100644
--- a/util/opentelemetry-util-http/setup.cfg
+++ b/util/opentelemetry-util-http/setup.cfg
@@ -40,8 +40,4 @@ package_dir=
 packages=find_namespace:
 
 [options.packages.find]
-where = src
-
-[options.entry_points]
-opentelemetry_instrumentor =
-    httplib = opentelemetry.util.http.httplib:HttpClientInstrumentor
+where = src
\ No newline at end of file