diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/CHANGELOG.md b/instrumentation-genai/opentelemetry-instrumentation-vertexai/CHANGELOG.md
index 4e43fbff1..44725df52 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/CHANGELOG.md
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/CHANGELOG.md
@@ -11,3 +11,5 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
   ([#3192](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3192))
 - Initial VertexAI instrumentation
   ([#3123](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3123))
+- Add server attributes to Vertex AI spans
+  ([#3208](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/3208))
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
index 36a31045b..ecb87e436 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/patch.py
@@ -25,6 +25,7 @@ from opentelemetry._events import EventLogger
 from opentelemetry.instrumentation.vertexai.utils import (
     GenerateContentParams,
     get_genai_request_attributes,
+    get_server_attributes,
     get_span_name,
 )
 from opentelemetry.trace import SpanKind, Tracer
@@ -100,7 +101,11 @@ def generate_content_create(
         kwargs: Any,
     ):
         params = _extract_params(*args, **kwargs)
-        span_attributes = get_genai_request_attributes(params)
+        api_endpoint: str = instance.api_endpoint  # type: ignore[reportUnknownMemberType]
+        span_attributes = {
+            **get_genai_request_attributes(params),
+            **get_server_attributes(api_endpoint),
+        }
 
         span_name = get_span_name(span_attributes)
         with tracer.start_as_current_span(
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
index 96d712502..e4297bc87 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/src/opentelemetry/instrumentation/vertexai/utils.py
@@ -22,10 +22,12 @@ from typing import (
     Mapping,
     Sequence,
 )
+from urllib.parse import urlparse
 
 from opentelemetry.semconv._incubating.attributes import (
     gen_ai_attributes as GenAIAttributes,
 )
+from opentelemetry.semconv.attributes import server_attributes
 from opentelemetry.util.types import AttributeValue
 
 if TYPE_CHECKING:
@@ -58,6 +60,24 @@ class GenerateContentParams:
     ) = None
 
 
+def get_server_attributes(
+    endpoint: str,
+) -> dict[str, AttributeValue]:
+    """Get server.* attributes from the endpoint, which is a hostname with optional port e.g.
+    - ``us-central1-aiplatform.googleapis.com``
+    - ``us-central1-aiplatform.googleapis.com:5431``
+    """
+    parsed = urlparse(f"scheme://{endpoint}")
+
+    if not parsed.hostname:
+        return {}
+
+    return {
+        server_attributes.SERVER_ADDRESS: parsed.hostname,
+        server_attributes.SERVER_PORT: parsed.port or 443,
+    }
+
+
 def get_genai_request_attributes(
     params: GenerateContentParams,
     operation_name: GenAIAttributes.GenAiOperationNameValues = GenAIAttributes.GenAiOperationNameValues.CHAT,
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_chat_completions.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_chat_completions.py
index 63a2e2c2d..2582a086f 100644
--- a/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_chat_completions.py
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_chat_completions.py
@@ -34,6 +34,8 @@ def test_generate_content(
         "gen_ai.operation.name": "chat",
         "gen_ai.request.model": "gemini-1.5-flash-002",
         "gen_ai.system": "vertex_ai",
+        "server.address": "us-central1-aiplatform.googleapis.com",
+        "server.port": 443,
     }
 
 
@@ -62,6 +64,8 @@ def test_generate_content_empty_model(
         "gen_ai.operation.name": "chat",
         "gen_ai.request.model": "",
         "gen_ai.system": "vertex_ai",
+        "server.address": "us-central1-aiplatform.googleapis.com",
+        "server.port": 443,
     }
     assert_span_error(spans[0])
 
@@ -91,6 +95,8 @@ def test_generate_content_missing_model(
         "gen_ai.operation.name": "chat",
         "gen_ai.request.model": "gemini-does-not-exist",
         "gen_ai.system": "vertex_ai",
+        "server.address": "us-central1-aiplatform.googleapis.com",
+        "server.port": 443,
     }
     assert_span_error(spans[0])
 
@@ -122,6 +128,8 @@ def test_generate_content_invalid_temperature(
         "gen_ai.request.model": "gemini-1.5-flash-002",
         "gen_ai.request.temperature": 1000.0,
         "gen_ai.system": "vertex_ai",
+        "server.address": "us-central1-aiplatform.googleapis.com",
+        "server.port": 443,
     }
     assert_span_error(spans[0])
 
@@ -158,6 +166,8 @@ def test_generate_content_extra_params(span_exporter, instrument_no_content):
         "gen_ai.request.temperature": 0.20000000298023224,
         "gen_ai.request.top_p": 0.949999988079071,
         "gen_ai.system": "vertex_ai",
+        "server.address": "us-central1-aiplatform.googleapis.com",
+        "server.port": 443,
     }
 
 
diff --git a/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_utils.py b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_utils.py
new file mode 100644
index 000000000..082ea72ad
--- /dev/null
+++ b/instrumentation-genai/opentelemetry-instrumentation-vertexai/tests/test_utils.py
@@ -0,0 +1,32 @@
+# Copyright The OpenTelemetry Authors
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     http://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+
+from opentelemetry.instrumentation.vertexai.utils import get_server_attributes
+
+
+def test_get_server_attributes() -> None:
+    # without port
+    assert get_server_attributes("us-central1-aiplatform.googleapis.com") == {
+        "server.address": "us-central1-aiplatform.googleapis.com",
+        "server.port": 443,
+    }
+
+    # with port
+    assert get_server_attributes(
+        "us-central1-aiplatform.googleapis.com:5432"
+    ) == {
+        "server.address": "us-central1-aiplatform.googleapis.com",
+        "server.port": 5432,
+    }