diff --git a/README.md b/README.md
index 4f291af..a367870 100644
--- a/README.md
+++ b/README.md
@@ -26,8 +26,6 @@ Tool for live presentations using either [Manim (community edition)](https://www
 
 While installing Manim Slides and its dependencies on your global Python is fine, I recommend using a [virtualenv](https://docs.python.org/3/tutorial/venv.html) for a local installation.
 
-> **_NOTE:_** Startin with version 4.2, Manim Slides seems to have **troubles installing on mac M1 chips**. An issue has been created [#53](https://github.com/jeertmans/manim-slides/issues/53), and we recommend following its evolution for any update.
-
 ### Dependencies
 
 Manim Slides requires either Manim or ManimGL to be installed. Having both packages installed is fine too.
@@ -90,7 +88,7 @@ class Example(Slide):
         self.play(dot.animate.move_to(ORIGIN))
         self.pause()  # Waits user to press continue to go to the next slide
 
-        self.wait()  # The presentation directly exits after last animation
+        self.wait()
 ```
 
 You **must** end your `Slide` with a `self.play(...)` or a `self.wait(...)`.
diff --git a/manim_slides/config.py b/manim_slides/config.py
index 47faf6e..fb8ddd4 100644
--- a/manim_slides/config.py
+++ b/manim_slides/config.py
@@ -3,7 +3,7 @@ from enum import Enum
 from typing import List, Optional, Set
 
 from pydantic import BaseModel, root_validator, validator
-from PyQt5.QtCore import Qt
+from PySide6.QtCore import Qt
 
 from .manim import logger
 
diff --git a/manim_slides/present.py b/manim_slides/present.py
index 00bbe2c..bcf962e 100644
--- a/manim_slides/present.py
+++ b/manim_slides/present.py
@@ -9,10 +9,10 @@ import click
 import cv2
 import numpy as np
 from pydantic import ValidationError
-from PyQt5 import QtGui
-from PyQt5.QtCore import Qt, QThread, pyqtSignal, pyqtSlot
-from PyQt5.QtGui import QPixmap
-from PyQt5.QtWidgets import QApplication, QGridLayout, QLabel, QWidget
+from PySide6 import QtGui
+from PySide6.QtCore import Qt, QThread, Signal, Slot
+from PySide6.QtGui import QPixmap
+from PySide6.QtWidgets import QApplication, QGridLayout, QLabel, QWidget
 from tqdm import tqdm
 
 from .commons import config_path_option, verbosity_option
@@ -282,9 +282,9 @@ class Presentation:
 class Display(QThread):
     """Displays one or more presentations one after each other."""
 
-    change_video_signal = pyqtSignal(np.ndarray)
-    change_info_signal = pyqtSignal(dict)
-    finished = pyqtSignal()
+    change_video_signal = Signal(np.ndarray)
+    change_info_signal = Signal(dict)
+    finished = Signal()
 
     def __init__(
         self,
@@ -409,7 +409,7 @@ class Display(QThread):
             }
         )
 
-    @pyqtSlot(int)
+    @Slot(int)
     def set_key(self, key: int) -> None:
         """Sets the next key to be handled."""
         self.key = key
@@ -484,7 +484,7 @@ class Info(QWidget):
 
         self.update_info({})
 
-    @pyqtSlot(dict)
+    @Slot(dict)
     def update_info(self, info: dict):
         self.animationLabel.setText("Animation: {}".format(info.get("animation", "na")))
         self.stateLabel.setText("State: {}".format(info.get("state", "unknown")))
@@ -517,7 +517,7 @@ class InfoThread(QThread):
 
 
 class App(QWidget):
-    send_key_signal = pyqtSignal(int)
+    send_key_signal = Signal(int)
 
     def __init__(
         self,
@@ -603,13 +603,13 @@ class App(QWidget):
         self.closeAll()
         event.accept()
 
-    @pyqtSlot(np.ndarray)
+    @Slot(np.ndarray)
     def update_image(self, cv_img: dict):
         """Updates the image_label with a new opencv image"""
         self.pixmap = self.convert_cv_qt(cv_img)
         self.label.setPixmap(self.pixmap)
 
-    @pyqtSlot(dict)
+    @Slot(dict)
     def update_info(self, info: dict):
         """Updates the image_label with a new opencv image"""
         pass
diff --git a/manim_slides/wizard.py b/manim_slides/wizard.py
index d9755b4..41b4ba8 100644
--- a/manim_slides/wizard.py
+++ b/manim_slides/wizard.py
@@ -4,8 +4,8 @@ from functools import partial
 from typing import Any
 
 import click
-from PyQt5.QtCore import Qt
-from PyQt5.QtWidgets import (
+from PySide6.QtCore import Qt
+from PySide6.QtWidgets import (
     QApplication,
     QDialog,
     QDialogButtonBox,
@@ -25,9 +25,8 @@ from .manim import logger
 WINDOW_NAME: str = "Configuration Wizard"
 
 keymap = {}
-for key, value in vars(Qt).items():
-    if isinstance(value, Qt.Key):
-        keymap[value] = key.partition("_")[2]
+for key in Qt.Key:
+    keymap[key.value] = key.name.partition("_")[2]
 
 
 class KeyInput(QDialog):
diff --git a/setup.py b/setup.py
index 059ec6a..ef781cb 100644
--- a/setup.py
+++ b/setup.py
@@ -39,7 +39,7 @@ setuptools.setup(
         "click-default-group>=1.2",
         "numpy>=1.19.3",
         "pydantic>=1.9.1",
-        "pyqt5>=5.15",
+        "pyside6>=6.4",
         "opencv-python>=4.6",
         "tqdm>=4.62.3",
     ],