diff --git a/BREAKING.md b/BREAKING.md
index 5b2febefe0..282814ae96 100644
--- a/BREAKING.md
+++ b/BREAKING.md
@@ -101,12 +101,16 @@ Converted `ion-modal` to use [Shadow DOM](https://developer.mozilla.org/en-US/do
 
 If you were targeting the internals of `ion-modal` in your CSS, you will need to target the `backdrop` or `content` [Shadow Parts](https://ionicframework.com/docs/theming/css-shadow-parts) instead, or use the provided CSS Variables.
 
+Developers dynamically creating modals using `document.createElement('ion-modal')` will now need to call `modal.remove()` after the modal has been dismissed if they want the modal to be removed from the DOM.
+
 #### Popover
 
 Converted `ion-popover` to use [Shadow DOM](https://developer.mozilla.org/en-US/docs/Web/Web_Components/Using_shadow_DOM).
 
 If you were targeting the internals of `ion-popover` in your CSS, you will need to target the `backdrop`, `arrow`, or `content` [Shadow Parts](https://ionicframework.com/docs/theming/css-shadow-parts) instead, or use the provided CSS Variables.
 
+Developers dynamically creating popovers using `document.createElement('ion-popover')` will now need to call `popover.remove()` after the popover has been dismissed if they want the popover to be removed from the DOM.
+
 #### Radio
 
 The `RadioChangeEventDetail` interface has been removed. Instead, listen for the `ionChange` event on `ion-radio-group` and use the `RadioGroupChangeEventDetail` interface.
diff --git a/core/src/components.d.ts b/core/src/components.d.ts
index b7ad27a934..49cd4308bf 100644
--- a/core/src/components.d.ts
+++ b/core/src/components.d.ts
@@ -1532,6 +1532,7 @@ export namespace Components {
           * The horizontal line that displays at the top of a sheet modal. It is `true` by default when setting the `breakpoints` and `initialBreakpoint` properties.
          */
         "handle"?: boolean;
+        "hasController": boolean;
         /**
           * Additional attributes to pass to the modal.
          */
@@ -1883,6 +1884,7 @@ export namespace Components {
          */
         "event": any;
         "getParentPopover": () => Promise<HTMLIonPopoverElement | null>;
+        "hasController": boolean;
         /**
           * Additional attributes to pass to the popover.
          */
@@ -5220,6 +5222,7 @@ declare namespace LocalJSX {
           * The horizontal line that displays at the top of a sheet modal. It is `true` by default when setting the `breakpoints` and `initialBreakpoint` properties.
          */
         "handle"?: boolean;
+        "hasController"?: boolean;
         /**
           * Additional attributes to pass to the modal.
          */
@@ -5509,6 +5512,7 @@ declare namespace LocalJSX {
           * The event to pass to the popover animation.
          */
         "event"?: any;
+        "hasController"?: boolean;
         /**
           * Additional attributes to pass to the popover.
          */
diff --git a/core/src/components/modal/modal.ios.scss b/core/src/components/modal/modal.ios.scss
index a5536aa1a6..d293f2500b 100644
--- a/core/src/components/modal/modal.ios.scss
+++ b/core/src/components/modal/modal.ios.scss
@@ -4,7 +4,7 @@
 // iOS Modals
 // --------------------------------------------------
 
-:host(:first-of-type) {
+:host {
   --backdrop-opacity: var(--ion-backdrop-opacity, 0.4);
 }
 
diff --git a/core/src/components/modal/modal.md.scss b/core/src/components/modal/modal.md.scss
index 3833e0fcf0..6a822e8918 100644
--- a/core/src/components/modal/modal.md.scss
+++ b/core/src/components/modal/modal.md.scss
@@ -5,16 +5,13 @@
 // Material Design Modals
 // --------------------------------------------------
 
-:host(:first-of-type) {
+:host {
   --backdrop-opacity: var(--ion-backdrop-opacity, 0.32);
 }
 
 @media only screen and (min-width: $modal-inset-min-width) and (min-height: $modal-inset-min-height-small) {
   :host {
     --border-radius: 2px;
-  }
-
-  :host(:first-of-type) {
     --box-shadow: #{$modal-inset-box-shadow};
   }
 }
@@ -24,3 +21,4 @@
 
   opacity: .01;
 }
+
diff --git a/core/src/components/modal/modal.tsx b/core/src/components/modal/modal.tsx
index 22fc85c8f1..37a08dec65 100644
--- a/core/src/components/modal/modal.tsx
+++ b/core/src/components/modal/modal.tsx
@@ -60,6 +60,9 @@ export class Modal implements ComponentInterface, OverlayInterface {
 
   @Element() el!: HTMLIonModalElement;
 
+  /** @internal */
+  @Prop() hasController = false;
+
   /** @internal */
   @Prop() overlayIndex!: number;
 
@@ -322,13 +325,13 @@ export class Modal implements ComponentInterface, OverlayInterface {
      * If using overlay inline
      * we potentially need to use the coreDelegate
      * so that this works in vanilla JS apps.
-     * If a user has already placed the overlay
-     * as a direct descendant of ion-app or
-     * the body, then we can assume that
-     * the overlay is already in the correct place.
+     * If a developer has presented this component
+     * via a controller, then we can assume
+     * the component is already in the
+     * correct place.
      */
     const parentEl = this.el.parentNode as HTMLElement | null;
-    const inline = this.inline = parentEl !== null && parentEl.tagName !== 'ION-APP' && parentEl.tagName !== 'BODY';
+    const inline = this.inline = parentEl !== null && !this.hasController;
     const delegate = this.workingDelegate = (inline) ? this.delegate || this.coreDelegate : this.delegate
 
     return { inline, delegate }
diff --git a/core/src/components/modal/test/sheet/index.html b/core/src/components/modal/test/sheet/index.html
index e841244bc0..7179436fa2 100644
--- a/core/src/components/modal/test/sheet/index.html
+++ b/core/src/components/modal/test/sheet/index.html
@@ -168,6 +168,9 @@
     async function presentModal(options) {
       const modal = createModal(options);
       await modal.present();
+
+      await modal.onDidDismiss();
+      modal.remove();
     }
 
     async function presentCardModal() {
diff --git a/core/src/components/popover/popover.tsx b/core/src/components/popover/popover.tsx
index 1944265061..ec2c723ce4 100644
--- a/core/src/components/popover/popover.tsx
+++ b/core/src/components/popover/popover.tsx
@@ -56,6 +56,9 @@ export class Popover implements ComponentInterface, PopoverInterface {
 
   @Element() el!: HTMLIonPopoverElement;
 
+  /** @internal */
+  @Prop() hasController = false;
+
   /** @internal */
   @Prop() delegate?: FrameworkDelegate;
 
@@ -337,13 +340,13 @@ export class Popover implements ComponentInterface, PopoverInterface {
      * If using overlay inline
      * we potentially need to use the coreDelegate
      * so that this works in vanilla JS apps.
-     * If a user has already placed the overlay
-     * as a direct descendant of ion-app or
-     * the body, then we can assume that
-     * the overlay is already in the correct place.
+     * If a developer has presented this component
+     * via a controller, then we can assume
+     * the component is already in the
+     * correct place.
      */
     const parentEl = this.el.parentNode as HTMLElement | null;
-    const inline = this.inline = parentEl !== null && parentEl.tagName !== 'ION-APP' && parentEl.tagName !== 'BODY';
+    const inline = this.inline = parentEl !== null && !this.hasController;
     const delegate = this.workingDelegate = (inline) ? this.delegate || this.coreDelegate : this.delegate
 
     return { inline, delegate }
diff --git a/core/src/css/core.scss b/core/src/css/core.scss
index 7e33f1f4d6..d3440a3583 100644
--- a/core/src/css/core.scss
+++ b/core/src/css/core.scss
@@ -86,6 +86,30 @@ html.ios ion-modal .ion-page {
   }
 }
 
+/**
+ * Subsequent modals should not have a backdrop/box shadow
+ * as it will cause the screen to appear to get progressively
+ * darker. With Ionic 6, declarative modals made it
+ * possible to have multiple non-presented modals in the DOM,
+ * so we could no longer rely on ion-modal:first-of-type.
+ * Here we disable the opacity/box-shadow for every modal
+ * that comes after the first presented modal.
+ *
+ * Note: ion-modal:not(.overlay-hidden):first-of-type
+ * does not match the first modal to not have
+ * the .overlay-hidden class, it will match the
+ * first modal in general only if it does not
+ * have the .overlay-hidden class.
+ * The :nth-child() pseudo-class has support
+ * for selectors which would help us here. At the
+ * time of writing it does not have great cross browser
+ * support.
+ */
+ion-modal:not(.overlay-hidden) ~ ion-modal {
+  --backdrop-opacity: 0;
+  --box-shadow: none;
+}
+
 // Ionic Colors
 // --------------------------------------------------
 // Generates the color classes and variables based on the
diff --git a/core/src/utils/overlays.ts b/core/src/utils/overlays.ts
index cc21b3bb62..050a2ecc89 100644
--- a/core/src/utils/overlays.ts
+++ b/core/src/utils/overlays.ts
@@ -54,7 +54,7 @@ export const createOverlay = <T extends HTMLIonOverlayElement>(tagName: string,
        * Convert the passed in overlay options into props
        * that get passed down into the new overlay.
        */
-      Object.assign(element, { ...opts });
+      Object.assign(element, { ...opts, hasController: true });
 
       // append the overlay element to the document body
       getAppRoot(document).appendChild(element);
diff --git a/core/src/utils/test/framework-delegate/framework-delegate.e2e.ts b/core/src/utils/test/framework-delegate/framework-delegate.e2e.ts
new file mode 100644
index 0000000000..70a9993f92
--- /dev/null
+++ b/core/src/utils/test/framework-delegate/framework-delegate.e2e.ts
@@ -0,0 +1,35 @@
+import { newE2EPage } from '@stencil/core/testing';
+
+test('framework-delegate: should present modal already at ion-app root', async () => {
+  const page = await newE2EPage({ url: '/src/utils/test/framework-delegate?ionic:_testing=true' });
+
+  const button = await page.find('#button-inline-root');
+  await button.click();
+
+  const modal = await page.find('#inline-root');
+  expect(modal).not.toBe(null);
+  await modal.waitForVisible();
+
+});
+
+test('framework-delegate: should present modal in content', async () => {
+  const page = await newE2EPage({ url: '/src/utils/test/framework-delegate?ionic:_testing=true' });
+
+  const button = await page.find('#button-inline-content');
+  await button.click();
+
+  const modal = await page.find('#inline-content');
+  expect(modal).not.toBe(null);
+  await modal.waitForVisible();
+});
+
+test('framework-delegate: should present modal via controller', async () => {
+  const page = await newE2EPage({ url: '/src/utils/test/framework-delegate?ionic:_testing=true' });
+
+  const button = await page.find('#button-controller');
+  await button.click();
+
+  const modal = await page.find('#controller');
+  expect(modal).not.toBe(null);
+  await modal.waitForVisible();
+});
diff --git a/core/src/utils/test/framework-delegate/index.html b/core/src/utils/test/framework-delegate/index.html
new file mode 100644
index 0000000000..43e51f0527
--- /dev/null
+++ b/core/src/utils/test/framework-delegate/index.html
@@ -0,0 +1,67 @@
+<!DOCTYPE html>
+<html lang="en" dir="ltr">
+  <head>
+    <meta charset="UTF-8">
+    <title>Framework Delegate</title>
+    <meta name="viewport" content="width=device-width, initial-scale=1.0, minimum-scale=1.0, maximum-scale=1.0, user-scalable=no, viewport-fit=cover">
+    <link href="../../../../../css/ionic.bundle.css" rel="stylesheet">
+    <link href="../../../../../scripts/testing/styles.css" rel="stylesheet">
+    <script type="module" src="../../../../../dist/ionic/ionic.esm.js"></script>
+    <script type="module">
+      import { modalController, createAnimation } from '../../../../../dist/ionic/index.esm.js';
+      window.modalController = modalController;
+    </script>
+  </head>
+  <body>
+    <ion-app>
+      <ion-modal id="inline-root" trigger="button-inline-root">
+        <ion-content class="ion-padding">
+          Hello World
+        </ion-content>
+      </ion-modal>
+      <div class="ion-page" id="main-content">
+        <ion-header>
+          <ion-toolbar>
+            <ion-title>Modal - Inline</ion-title>
+          </ion-toolbar>
+        </ion-header>
+
+        <ion-content class="ion-padding">
+          <ion-button id="button-inline-root">Open inline modal at ion-app root</ion-button>
+          <ion-button id="button-inline-content">Open inline modal inside of content</ion-button>
+          <ion-button id="button-controller" onclick="createAndPresentModal()">Open controller modal</ion-button>
+
+          <ion-modal id="inline-content" trigger="button-inline-content">
+            <ion-content class="ion-padding">
+              Hello World
+            </ion-content>
+          </ion-modal>
+        </ion-content>
+      </div>
+    </ion-app>
+
+    <script>
+      const createModal = async () => {
+        const div = document.createElement('div');
+        div.innerHTML = `
+          <ion-content class="ion-padding">
+            Hello World
+          </ion-content>
+        `;
+
+        const modal = await modalController.create({
+          component: div,
+          id: 'controller'
+        });
+
+        return modal;
+      }
+
+      const createAndPresentModal = async () => {
+        const modal = await createModal();
+        await modal.present();
+      }
+    </script>
+
+  </body>
+</html>