diff --git a/core/src/components/buttons/buttons.tsx b/core/src/components/buttons/buttons.tsx
index e826ec7633..7cf672d7bd 100644
--- a/core/src/components/buttons/buttons.tsx
+++ b/core/src/components/buttons/buttons.tsx
@@ -34,7 +34,9 @@ export class Buttons implements ComponentInterface {
           [mode]: true,
           ['buttons-collapse']: this.collapse,
         }}
-      ></Host>
+      >
+        <slot></slot>
+      </Host>
     );
   }
 }
diff --git a/core/src/components/label/label.tsx b/core/src/components/label/label.tsx
index 1cfe88ffb7..6f8ad05a4a 100644
--- a/core/src/components/label/label.tsx
+++ b/core/src/components/label/label.tsx
@@ -107,7 +107,9 @@ export class Label implements ComponentInterface {
           [`label-no-animate`]: this.noAnimate,
           'label-rtl': document.dir === 'rtl',
         })}
-      ></Host>
+      >
+        <slot></slot>
+      </Host>
     );
   }
 }
diff --git a/core/src/utils/slot-mutation-controller.ts b/core/src/utils/slot-mutation-controller.ts
index 3827c28f9f..c07f2da5f2 100644
--- a/core/src/utils/slot-mutation-controller.ts
+++ b/core/src/utils/slot-mutation-controller.ts
@@ -50,6 +50,18 @@ export const createSlotMutationController = (
 
     hostMutationObserver.observe(el, {
       childList: true,
+      /**
+       * This fixes an issue with the `ion-input` and
+       * `ion-textarea` not re-rendering in some cases
+       * when using the label slot functionality.
+       *
+       * HTML element patches in Stencil that are enabled
+       * by the `experimentalSlotFixes` flag in Stencil v4
+       * result in DOM manipulations that won't trigger
+       * the current mutation observer configuration and
+       * callback.
+       */
+      subtree: true,
     });
   }
 
diff --git a/core/stencil.config.ts b/core/stencil.config.ts
index 78a3697a07..2485eafb23 100644
--- a/core/stencil.config.ts
+++ b/core/stencil.config.ts
@@ -257,4 +257,18 @@ export const config: Config = {
   globalScript: 'src/global/ionic-global.ts',
   enableCache: true,
   transformAliasedImportPaths: true,
+  extras: {
+    /**
+     * `experimentalSlotFixes` is necessary in Stencil v4 until the fixes described in
+     * {@link https://stenciljs.com/docs/config-extras#experimentalslotfixes the Stencil docs for the flag} are the
+     * default behavior (slated for a future Stencil major version).
+     */
+    experimentalSlotFixes: true,
+    /**
+     * `experimentalScopedSlotChanges` is necessary in Stencil v4 until the fixes described in
+     * {@link https://stenciljs.com/docs/config-extras#experimentalscopedslotchanges the Stencil docs for the flag} are
+     * the default behavior (slated for a future Stencil major version).
+     */
+    experimentalScopedSlotChanges: true,
+  }
 };