diff --git a/packages/components/autocomplete/src/autocomplete.vue b/packages/components/autocomplete/src/autocomplete.vue
index 4de63d43c0..8f6e4b4502 100644
--- a/packages/components/autocomplete/src/autocomplete.vue
+++ b/packages/components/autocomplete/src/autocomplete.vue
@@ -357,6 +357,8 @@ const highlight = (index: number) => {
 }
 
 const stopHandle = onClickOutside(listboxRef, () => {
+  // Prevent closing if focus is inside popper content
+  if (popperRef.value?.isFocusInsideContent()) return
   suggestionVisible.value && close()
 })